Microdrop microfluidics is an emerging technology for high throughput screening and processing of biological systems ranging from directed evolution to protein crystallization. Our team has implemented merging, interrogation, and sorting of droplets for the NSF Materials Research Science and Engineering Center at Brandeis. To do so, we developed a series of microfluidic chips and a test stand capable of actuating sorting in real time based on fluorescence levels, enabling Brandeis to pursue new directions of research.