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Care and Liberation in Creating a Student-Led Public Interest Technology Clinic

Last modified
Tuesday, May 31, 2022 - 12:25
In Faculty Publications

Description

The emerging field of Public Interest Technology contains the seeds for an engineering practice that embodies the ethic of care and undergraduate engineering educational experiences in the mold of liberatory education. We realized these opportunities by creating an undergraduate, student-led public interest technology clinic. Using autoethnography, we reflect on our effort to create the clinic and find that we prioritized emotions and relationships, embraced slowness and deliberation, and claimed student ownership. These practices served to redefine engineering in ways that center care and equity, helping us create the inclusive and effective engineering and public interest technology educational experiences we wanted for ourselves.

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Resisting Crisis Surveillance Capitalism in Academic Libraries

Last modified
Friday, January 7, 2022 - 15:29
In Faculty Publications

Description

In this paper, we consider what we identify as crisis surveillance capitalism in higher education, drawing on the work of Naomi Klein and Shoshana Zuboff. We define crisis surveillance capitalism as the intersection of unregulated and ubiquitous data collection with the continued marginalization of vulnerable racial and social groups. Through this lens, we examine the twinned crisis narratives of student success and academic integrity and consider how the COVID-19 pandemic further enabled so-called solutions that collect massive amounts of student data with impunity. We suggest a framework of refusal to crisis surveillance capitalism coming from the work of Keller Easterling and Baharak Yousefi, identifying ways to resist and build power in a context where the cause of harm is all around and intentionally hidden.

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Pericellular Conditions Regulate Extent of Cell-Mediated Compaction of Collagen Gels

Last modified
Friday, July 9, 2021 - 12:39
In Faculty Publications

Description

Cell-mediated compaction of the extracellular matrix (ECM) plays a critical role in tissue engineering, woundhealing, embryonic development, and many disease states. The ECM is compacted as a result of cellular traction forces. Wehypothesize that a cell mechanically remodels the nearby ECM until some target conditions are obtained, and then the cell stopscompacting. A key feature of this hypothesis is that ECM compaction primarily occurs in the pericellular region and the propertiesof the ECM in the pericellular region govern cellular force generation. We developed a mathematical model to describe theamount of macroscopic compaction of cell-populated collagen gels in terms of the initial cell and collagen densities, as wellas the final conditions of the pericellular environment (defined as the pericellular volume where the collagen is compacted(V) and the mass of collagen within this volume (m)). This model qualitatively predicts the effects of varying initial cell andcollagen concentrations on the extent of gel compaction, and by fitting V and m, provides reasonable quantitative agreementwith the extent of gel compaction observed in experiments with endothelial cells and fibroblasts. Microscopic analysis ofcompacted gels supports the assumption that collagen compaction occurs primarily in the pericellular environment.

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Mapping a Gene for Familial Hypertrophic Cardiomyopathy to Chromosome 14q1

Last modified
Thursday, December 3, 2020 - 17:33
In Faculty Publications

Description

To identify the chromosomal location of a gene responsible for familial hypertrophic cardiomyopathy, we used clinical and molecular genetic techniques to evaluate the members of a large kindred. Twenty surviving and 24 deceased family members had hypertrophic cardiomyopathy; 58 surviving members were unaffected. Genetic-linkage analyses were performed with polymorphic DNA loci dispersed throughout the entire genome, to identify a locus that was inherited with hypertrophic cardiomyopathy in family members. The significance of the linkage detected between the disease locus and polymorphic loci was assessed by calculating a lod score (the logarithm of the probability of observing coinheritance of two loci, assuming that they are genetically linked, divided by the probability of detecting coinheritance if they are unlinked). A DNA locus (D14S26), previously mapped to chromosome 14 and of unknown function, was found to be coinherited with the disease in this family. No instances of recombination were observed between the locus for familial hypertrophic cardiomyopathy and D14S26, yielding a lod score of +9.37 (θ= 0). These data indicate that in this kindred, the odds are greater than 2,000,000,000:1 that the gene responsible for familial hypertrophic cardiomyopathy is located on chromosome 14 (band q1).

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Electrochemistry and staging in La2CuO4+d

Last modified
Thursday, December 3, 2020 - 17:33
In Faculty Publications

Description

Measurements are reported of the time dependence of the current during electrochemical oxidation and reduction at a fixed voltage of single crystals and ceramic samples of La2CuO4+d. Staging peaks in neutron measurements of the single crystals together with the electrochemical measurements and magnetization measurements confirm that stage n=6 corresponds to d=0.055 +/- 0.05, the high-d side of the oxygen-rich–oxygen-poor miscibility gap. Furthermore, stage n=4 occurs at a value of d consistent with d { n^(-1). For ceramic samples it is shown that two different superconducting compounds are formed depending on the oxidation voltage used.

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Two-magnon excitations observed by neutron scattering in the two-dimensional spin-5/2 Heisenberg antiferromagnet Rb2MnF4

Last modified
Thursday, December 3, 2020 - 17:32
In Faculty Publications

Description

The low-temperature magnetic excitations of the two-dimensional spin- 52 square-lattice Heisenberg antiferromagnetRb2MnF4 have been probed using pulsed inelastic neutron scattering. In addition to dominant sharppeaks identified with one-magnon excitations, a relatively weak continuum scattering is also observed at higherenergies. This is attributed to neutron scattering by pairs of magnons and the observed intensities are consistentwith predictions of spin wave theory.

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Spin Correlations in an Isotropic Spin-5/2 Two-Dimensional Antiferromagnet

Last modified
Thursday, December 3, 2020 - 17:31
In Faculty Publications

Description

We report a neutron scattering study of the spin correlations for the spin-5/2 two-dimensional antiferromagnet Rb2MnF4 in an external magnetic field. Choosing fields near the system’s bicritical point, we tune the effective anisotropy in the spin interaction to zero, constructing an ideal S ­ = 5/2 Heisenberg system. The correlation length and structure factor amplitude are closely described by the semiclassical theory of Cuccoli 'et al.' over a broad temperature range, but show no indication of approaching the low-temperature renormalized classical regime of the quantum nonlinear sigma model.

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X-ray Scattering Studies of Two Length Scales in the Critical Fluctuations of CuGeO3

Last modified
Thursday, December 3, 2020 - 17:31
In Faculty Publications

Description

The critical fluctuations of CuGeO3 have been measured by synchrotron x-ray scattering, and two length scales are clearly observed. The ratio between the two length scales is found to be significantly different along the a axis, with the a axis along the surface normal direction. We believe that such a directional preference is a clear sign that random surface strains, especially those caused by dislocations, are the origin of the long length scale fluctuations.

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Spinodal Decomposition in a Model Colloid-Polymer Mixture in Microgravity

Last modified
Thursday, December 3, 2020 - 17:30
In Faculty Publications

Description

We study phase separation in a deeply quenched colloid-polymer mixture in microgravity on the International Space Station using small-angle light scattering and direct imaging. We observe a clear crossover from early-stage spinodal decomposition to late-stage, interfacial-tension-driven coarsening. Data acquired over 5 orders of magnitude in time show more than 3 orders of magnitude increase in domain size, following nearly the same evolution as that in binary liquid mixtures. The late-stage growth approaches the expected linear growth rate quite slowly.

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If Emulation is Representation, Does Detail Matter?

Last modified
Thursday, December 3, 2020 - 17:30
In Faculty Publications

Description

One property of the emulator framework presented by Grush is that imagery operates off-line. Contrary to this viewpoint, we present evidence showing that mental rotation of a simple figure modulates low-level features of drawing articulation. This effect is dependent upon the type of rotation, suggesting a more integrative online role for imagery than proposed by the target article.

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Mapping the gene for hereditary cutaneous malignant melanoma-dysplastic nevus to chromosome 1p

Last modified
Thursday, December 3, 2020 - 17:29
In Faculty Publications

Description

We used molecular genetic techniques and multipoint linkage analyses to locate the gene responsible for cutaneous malignant melanoma-dysplastic nevus. We evaluated 99 relatives and 26 spouses in six families with a predisposition to melanoma. Thirty-four family members had cutaneous malignant melanoma, and 31 of these 34 also had histologically confirmed dysplastic nevi. Twenty-four family members had dysplastic nevi alone. An analysis of the cosegregation of the cutaneous malignant melanoma–dysplastic nevus trait with 26 polymorphic DNA markers on the short arm of chromosome 1 demonstrated the presence of a gene for susceptibility to melanoma. The gene was located between an anonymous DNA marker (D1S47) and the gene locus for pronatrodilatin, a commonly used reference gene (PND), in chromosome band 1p36. The odds were greater than 260,000:1 in favor of linkage at this location.

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Limits to Gelation in Colloidal Aggregation

Last modified
Thursday, December 3, 2020 - 17:28
In Faculty Publications

Description

We show that the dynamics of large fractal colloid aggregates are well described by a combination of translational and rotational diffusion and internal elastic fluctuations, allowing both the aggregate size and internal elasticity to be determined by dynamic light scattering. The comparison of results obtained in microgravity and on Earth demonstrates that cluster growth is limited by gravity-induced restructuring. In the absence of gravity, thermal fluctuations ultimately inhibit fractal growth and set the fundamental limitation to the lowest volume fraction which will gel.

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Time-dependent strength of colloidal gels

Last modified
Wednesday, December 2, 2020 - 16:41
In Faculty Publications

Description

Colloidal silica gels are shown to stiffen with time, as demonstrated by both dynamic light scattering and bulk rheological measurements. Their elastic moduli increase as a power law with time, independent of particle volume fraction; however, static light scattering indicates that there are no large-scale structural changes. We propose that increases in local elasticity arising from bonding between neighboring colloidal particles can account for the strengthening of the network, while preserving network structure.

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Ena/VASP is required for endothelial barrier function in vivo

Last modified
Wednesday, December 2, 2020 - 16:39
In Faculty Publications

Description

Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) proteins are key actin regulators that localize at regions of dynamic actin remodeling, including cellular protrusions and cell-cell and cell-matrix junctions. Several studies have suggested that Ena/VASP proteins are involved in the formation and function of cellular junctions. Here, we establish the importance of Ena/VASP in endothelial junctions in vivo by analysis of Ena/VASP-deficient animals. In the absence of Ena/VASP, the vasculature exhibits patterning defects and lacks structural integrity, leading to edema, hemorrhaging, and late stage embryonic lethality. In endothelial cells, we find that Ena/VASP activity is required for normal F-actin content, actomyosin contractility, and proper response to shear stress. These findings demonstrate that Ena/VASP is critical for actin cytoskeleton remodeling events involved in the maintenance of functional endothelia.

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X-ray scattering study of the incommensurate phase in Mg-doped CuGeO3

Last modified
Wednesday, December 2, 2020 - 16:35
In Faculty Publications

Description

We present results of a systematic x-ray scattering study of the effects of Mg doping on the high-fieldincommensurate phase of CuGeO3. Lorentzian-squared line shapes, the changing of the first-order transition tosecond order, and the destruction of long-range order with infinitesimal doping are observed, consistent withrandom-field effects in a three-dimensional XY system. Values for the soliton width in pure and lightly dopedCuGeO3 are deduced. We find that even a very small doping has a drastic effect on the shape of the latticemodulation.

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Nonlinear electrokinetics at large voltages

Last modified
Wednesday, December 2, 2020 - 16:35
In Faculty Publications

Description

Part of Focus on Micro- and Nanofluidics The classical theory of electrokinetic phenomena assumes a dilute solution of point-like ions in chemical equilibrium with a surface whose double-layer voltage is of order the thermal voltage, kBT/e=25 mV. In nonlinear 'induced-charge' electrokinetic phenomena, such as ac electro-osmosis, several volts 100kBT/e are applied to the double layer, and the theory breaks down and cannot explain many observed features. We argue that, under such a large voltage, counterions 'condense' near the surface, even for dilute bulk solutions. Based on simple models, we predict that the double-layer capacitance decreases and the electro-osmotic mobility saturates at large voltages, due to steric repulsion and increased viscosity of the condensed layer, respectively. The former suffices to explain observed high-frequency flow reversal in ac electro-osmosis; the latter leads to a salt concentration dependence of induced-charge flows comparable to experiments, although a complete theory is still lacking.

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Critical dynamics of a spin-5/2 two-dimensional isotropic antiferromagnet

Last modified
Wednesday, December 2, 2020 - 16:32
In Faculty Publications

Description

We report a neutron-scattering study of the dynamic spin correlations in Rb2MnF4, a two-dimensional spin-5/2 antiferromagnet. By tuning an external magnetic field to the value for the spin-flop line, we reduce the effective spin anisotropy to essentially zero, thereby obtaining a nearly ideal two-dimensional isotropic antiferromagnet. From the shape of the quasielastic peak as a function of temperature, we demonstrate dynamic scaling for this system and find a value for the dynamical exponent z. We compare these results to theoretical predictions for the dynamic behavior of the two-dimensional Heisenberg model, in which deviations from z=1 provide a measure of the corrections to scaling.

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CAPS: Smoothly Transitioning to a More ResilientWeb PKI

Last modified
Thursday, October 29, 2020 - 12:29
In Faculty Publications

Description

Many recent proposals to increase the resilience of the Web PKI against misbehaving CAs face significant obstacles to deployment. These hurdles include (1) the requirement of drastic changes to the existing PKI players and their interactions, (2) the lack of signaling mechanisms to protect against downgrade attacks, (3) the lack of an incremental deployment strategy, and (4) the use of inflexible mechanisms that hinder recovery from misconfiguration or from the loss or compromise of private keys. As a result, few of these proposals have seen widespread deployment, despite their promise of a more secure Web PKI. To address these roadblocks, we propose Certificates with Automated Policies and Signaling (CAPS), a system that leverages the infrastructure of the existing Web PKI to overcome the aforementioned hurdles. CAPS offers a seamless and secure transition away from today’s insecure Web PKI and towards present and future proposals to improve the Web PKI. Crucially, with CAPS, domains can take simple steps to protect themselves from MITM attacks in the presence of one or more misbehaving CAs, and yet the interaction between domains and CAs remains fundamentally the same. We implement CAPS and show that it adds at most 5% to connection establishment latency.

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Musical Variations from a Chaotic Mapping

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

Description

A chaotic mapping provides a technique for generating musical variations of an original work. Thistechnique, based on the sensitivity of chaotic trajectories to initial conditions, produces changes inthe pitch sequence of a piece. A sequence of musical pitches $pi%, i.e., any piece ranging from Bach~or earlier! to contemporary music, is paired with the x-components $xi% of a Lorenz chaotictrajectory. Each pi is marked on the x axis at the point designated by its xi . In this way, the x axisbecomes a pitch axis configured according to the notes of the original composition. Then, a secondchaotic trajectory, whose initial condition differs from the first, is launched. Its x-componentstrigger pitches on the pitch axis ~via the mapping! that vary in sequence from the original work, thuscreating a variation. There are virtually an unlimited number of variations possible, many appealingto expert and nonexpert alike.

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Engineering Design Thinking, Teaching, and Learning

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

Description

This paper is based on the premises that the purpose of engineering education is to graduate engineers who can design, and that design thinking is complex. The paper begins by briefly reviewing the history and role of design in the engineering curriculum. Several dimensions of design thinking are then detailed, explaining why design is hard to learn and harder still to teach, and outlining the research available on how well design thinking skills are learned. The currently most-favored pedagogical model for teaching design, project-based learning (PBL), is explored next, along with available assessment data on its success. Two contexts for PBL are emphasized: first-year cornerstone courses and globally dispersed PBL courses. Finally, the paper lists some of the open research questions that must be answered to identify the best pedagogical practices of improving design learning, after which it closes by making recommendations for research aimed at enhancing design learning.

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Two-Magnon Excitations Observed by Neutron Scattering in the Two-Dimensional Spin-5/2 Heisenberg Antiferromagnet Rb2MnF4

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

Description

The low-temperature magnetic excitations of the two-dimensional spin-5/2 square-lattice Heisenberg antiferromagnet Rb2MnF4 have been probed using pulsed inelastic neutron scattering. In addition to dominant sharp peaks identified with one-magnon excitations, a relatively weak continuum scattering is also observed at higher energies. This is attributed to neutron scattering by pairs of magnons and the observed intensities are consistent with predictions of spin wave theory.

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Electrokinetic Instabilities in Thin Microchannels

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

Description

An important class of electrokinetic, microfluidic devices aims to pump and control electrolyte working liquids that have spatial gradients in conductivity. These high-gradient flows can become unstable under the application of a sufficiently strong electric field. In many of these designs, flow channels are thin in the direction orthogonal to the main flow and the conductivity gradient. Viscous stresses due to the presence of these walls introduce a stabilizing force that plays a major role in determining the overall instability. A thin channel model for fluid flow is developed and shown to provide good agreement with a complete three-dimensional model for channel aspect ratios less than or similar to 0.1.

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Online Engineering Education: Learning Anywhere, Anytime

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

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The emergence of worldwide communications networks and powerful computer technologies has redefined the concept of distance learning and the delivery of engineering education content. This article discusses the Sloan Consortium’s quest for quality, scale, and breadth in online learning, the impact on both continuing education of graduate engineers as well as degree-seeking engineering students, and the future of engineering colleges and schools as worldwide providers of engineering education.

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On Undercompressive Shocks and Flooding in Countercurrent Two-Layer Flows

Last modified
Wednesday, August 12, 2020 - 15:22
In Faculty Publications

Description

We consider the countercurrent flow of two incompressible immiscible viscous fluids in an inclined channel. This configuration may lead to the phenomena of ‘flooding’, i.e. the transition from a countercurrent regime to a cocurrent regime. This transition is marked by a variety of transient behaviour, such as the development of largeamplitude waves that impede the flow of one of the fluids to the reversal of the flow of the denser fluid. From a lubrication approximation based on the ratio of the channel height to the downstream disturbance wavelength, we derive a nonlinear system of evolution equations that govern the interfacial shape separating the two fluids and the leading-order pressure. This system, which assumes fluids with disparate density and dynamic viscosity ratios, includes the effects of viscosity stratification, inertia, shear and capillarity. Since the experimental constraints for this effective system are unclear, we consider two ways to drive the flow: either by fixing the volumetric flow rate of the gas phase or by fixing the total pressure drop over a downstream length of the channel. The latter forcing results in a single evolution equation whose dynamics depends non-locally on the interfacial shape. From both of these driven systems, admissible criteria for Lax shocks, undercompressive shocks and rarefaction waves are investigated. These criteria, through a numerical verification, do not depend significantly on the inertial effects within the more dense layer. The choice of the local/nonlocal constraints appears to play a role in the transient growth of undercompressive shocks, and may relate to the phenomena observed near the onset of flooding.

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Time-Dependent Strength of Colloidal Gels

Last modified
Wednesday, August 12, 2020 - 15:21
In Faculty Publications

Description

Colloidal silica gels are shown to stiffen with time, as demonstrated by both dynamic light scattering and bulk rheological measurements. Their elastic moduli increase as a power law with time, independent of particle volume fraction; however, static light scattering indicates that there are no large-scale structural changes. We propose that increases in local elasticity arising from bonding between neighboring colloidal particles can account for the strengthening of the network, while preserving network structure.

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  • Benchmark testing the Digital Imaging Network-Picture Archiving and Communications System proposal of the Department of Defense. (1)
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  • Collagen Gels with Different Fibrillar Microarchitectures Elicit Different Cellular Responses (1)
  • Colloid-polymer mixtures in the presence of quenched disorder: a theoretical and computer simulation study. (1)
  • Colloidal aggregation affects the efficacy of anticancer drugs in cell culture (1)
  • Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects. (1)
  • Concentration gradients for HVA, 5-HIAA, ascorbic acid, and uric acid in cerebrospinal fluid. (1)
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  • Electromagnetic energy harvesting based on HfZrO tunneling junctions (1)
  • Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress (1)
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  • Granular Media Calcinosis in the Aortic Walls of Patients With Bicuspid and Tricuspid Aortic Valves. (1)
  • Green's function (1)
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  • Inhomogeneities in the chemical structure of sugarcane bagasse lignin. (1)
  • Magnetic phase transitions in Pr(1-x)Lu(x)Mn(2)Ge(2) compounds. (1)
  • Mode-locked lasers: measurements of very fast radiative decay in fluorescent systems. (1)
  • Nonlinear Oscillations, Dynamical Systems, and Bifurcations of Vector Fields (1)
  • Online degrees for nurses: a flexible alternative. (1)
  • Perceptions (1)
  • Pericellular proteases in angiogenesis and vasculogenesis. (1)

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  • March 2018 (72)
  • August 2019 (3)

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An undergraduate engineering institution exploring innovative approaches to engineering education since its founding in 1997.

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